Avestin EmulsiFlex-C5 High Pressure Homogenizer

Description

This listing is for the Avestin EmulsiFlex-C5 for homogenizer with sealed toolings and spares The unit is in full working condition and is ready for immediate use EmulsiFlex-C5 High Pressure Homogenizer The Avestin EmulsiFlex-C5 is a high-pressure, pneumatically powered homogenizer designed for laboratory-scale applications. It is ideal for processing small to medium sample volumes, from 7 mL up to 5 L/h, depending on the pressure applied. How It Works: High Pressure Homogenisation High pressure homogenisation is an efficient and easy-to-use technique for cell disruption and liposome/emulsion processing. The principle involves pumping the sample through a valve with a small aperture. The sample transitions from very high pressure (up to 30,000 psi) on the pump side to atmospheric pressure on the outlet side. This sudden drop in pressure creates intense shear forces, disrupting cell membranes or dramatically reducing liposome/emulsion sizes. For cells, the pressure-induced shear forces rupture the membranes, effectively lysing the cells. For liposomes and emulsions, this process reduces their size from micron to nanometer range, often resulting in uniform particles with narrow size distributions. Unique Features of the EmulsiFlex-C5 Dynamic Homogenising Valve The C5 uses a dynamic homogenising valve, which maintains constant pressure during sample processing. This consistency ensures the formation of highly uniform liposomes and micro-emulsions, with tight particle size distributions. Efficient Cell Disruption Most cells (including E. coli) can be lysed in a single pass, minimizing over-processing and reducing the risk of protein denaturation or degradation. Pressure Range: Adjustable from 500 to 30,000 psi Flow Rate: 1–5 L/h depending on pressure Minimum Sample Volume: 7 mL Holdback Volume: Less than 1 mL Temperature Control: Can be used with ice baths, external chillers, or in cold rooms Autoclavable: Easy cleaning and sterilization (SIP-compatible) Compact Size: 430 × 160 × 320 mm, 25 kg Power Source: Requires compressed or bottled air. For most applications (e.g., E. coli disruption or liposome formation), 100 psi air pressure is sufficient. Applications Disruption of bacterial, yeast, algal, insect, or mammalian cells Nano-sized liposome and emulsion formation Particle size reduction in pharmaceuticals, cosmetics, and food products Liposomal drug delivery systems Efficient homogenisation for biochemical and biophysical research