Synthecon RCCS-4D Rotary Cell Culture Bioreactor System

Description

The Rotary Cell Culture System (RCCS) is a unique 3D cell culture technology for culturing both suspension and anchorage-dependent cells. It is the first bioreactor system designed to simultaneously integrate the ability to co-culture cells, and the features of low shear force (and consequently low turbulence), and high mass transfer of nutrients. Together these properties encourage spheroid formation and proliferation of cells within the three-dimensional spheroids. The RCCS-4D bioreactors is capable of rotating four vessels at the same speed; the rotation speed is adjustable. This system is only compatible with disposable vessels. RCCS FEATURES: Ability to co-culture multiple cell types in a 3D spheroid morphology Can be used with or without scaffolds to generate 3D cell models Low shear force in the rotating vessel (low turbulence) allows spheroid growth High mass transfer of nutrients in media prevents cell death within spheroid core Ability to vary rotation speed with tachometer 3D CELL CULTURE APPLICATIONS USING THE RCCS: Stem Cell Maintanance Stem Cell Expansion Stem Cell Differentiation Host-Pathogen Studies Cancer Modeling/ Tumor Spheroid Culture Cancer Cell Invasion Studies Tissue Engineering Spheroid Formation and Culture Recellularization Decellularization Explant Culture Organoid Culture