Unchained Labs Uncle Protein Stability Analyser, image 1
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VerifiedPre-ownedGood

Unchained Labs Uncle Protein Stability Analyser

Unchained Labs · Uncle · 2018 · ref ML-7DBC9590

Price

$16,500

+VAT where applicable

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Description

About this model

Benchtop protein stability analyser that combines full-spectrum fluorescence, static light scattering (SLS) and dynamic light scattering (DLS) in one instrument. It measures thermal melting (Tm), aggregation onset (Tagg), particle size and polydispersity on up to 48 samples per run, using 9 µL of sample in sealed capillary cassettes (Unis). Supports thermal ramp, isothermal and DSF dye-based methods, plus viscosity, kD, B22 and G22 applications.

This unit

Unchained Labs Uncle protein stability analyser, manufactured in November 2018. It combines full-spectrum fluorescence, SLS and DLS to measure Tm, Tagg and particle size on up to 48 samples of 9 µL per run. Condition and testing: used. The photos show the front power button illuminated and coolant present in the reservoir sight window. The exterior is clean with no visible damage. Software and computer: not included.

What's Included

Uncle instrument

Pre-owned equipment sold by a third-party reseller through MerkaLoop. Ships directly from the reseller.

Specifications

Condition
Good
Year Manufactured
2018
Manufacturer
Unchained Labs
Model
Uncle
Fuse
T6.3AL, 250 V
Weight
50 kg
Voltage
110 to 240 V AC, 50 to 60 Hz, single phase
Regulatory
Optional 21 CFR Part 11 software
Consumables
Uni sample cassettes
Laser Class
Class 1 laser product
DLS Detector
Avalanche photodiode
Heating Rate
0.1 to 10 °C/min
Tm Precision
<2% CV
Maximum Power
600 W
SLS Detection
Intensity at 266 nm and 473 nm
SLS Resolution
About 15 kDa change in mean molecular mass
Samples Per Run
48
AAV Concentration
≥5 x 10^11 viral genomes per mL
DLS Size Accuracy
±2%
Excitation Lasers
266 nm and 473 nm
Temperature Accuracy
±0.1 °C
Minimum Sample Volume
9 µL
Dimensions (W X D X H)
54 x 50 x 58 cm
Fluorescence Detection
CCD spectrometer, 250 to 720 nm
Measurement Techniques
Full-spectrum fluorescence, static light scattering, dynamic light scattering
Sample Temperature Range
15 to 95 °C
DLS Molecular Weight Range
192 Da to 25 MDa
Sample Concentration Range
0.05 to 300 mg/mL IgG
DLS Hydrodynamic Diameter Range
0.3 to 1000 nm
DLS Minimum Sample Concentration
0.1 mg/mL
Rating Plate
100-240 V, 50-60 Hz, 6 A, 600 W, Class 1 laser product
Date Of Manufacture
November 2018

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